Selected Papers by VLA Scientists
Transmissible Spongiform Encephalopathies
Allison GG, Horton RA, Stevens PR, Jackman R, Moorby JM 2007
Changes in plasma metabolites and muscle glycogen are correlated to bovine spongiform encephalopathy in infected dairy cattle.
Research in Veterinary Science 83 (1) 40-46.
Arnold ME, Ryan JBM,Konold T, Simmons MM, Spencer YI, Wear A, Chaplin M, Stack M, Czub S, Mueller R, Webb PR, Davis A, Spiropoulos J, Holdaway J, Hawkins SAC, Austin AR, Wells GAH 2007
Estimating the temporal relationship between PrPSc detection and incubation period in experimental bovine spongiform encephalopathy of cattle.
Journal of General Virology 88 (11) 3198-3208.
Bilheude JM, Brun A, Morel N, Diaz San Segundo F, Lecroix S, Espinosa JC, Gonzalez L, Steele P, Grassi J, Andreoletti O, Torres JM 2007
Discrimination of sheep susceptible and resistant to transmissible spongiform encephalopathies by an haplotype specific monoclonal antibody.
Journal of Virological Methods 145 (2) 169-172.
Bohning D, Del Rio Vilas VJ 2008
Estimating the hidden number of scrapie affected holdings in Great Britain using a simple, truncated count model allowing for heterogeneity.
Journal of Agricultural, Biological and Environmental Statistics 13 (1) 1-22.
Cummins E, Adkin A 2007
Exposure assessment of TSEs from the landspreading of meat and bone meal.
Risk Analysis 27 (5) 1179-1202.
Del Rio Vilas VJ, Hopp P, Nunes T, Ru G, Sivam K, Ortiz-Pelaez A 2007
Explaining the heterogeneous scrapie surveillance figures across Europe: a meta-regression approach.
BMC Veterinary Research 3 (13).
Everest DJ, Waterhouse S, Kelly T, Velo-Rego E, Sauer MJ 2007
Effectiveness of capillary electrophoresis fluoroimmunoassay of blood PrPSc for evaluation of scrapie pathogenesis in sheep.
Journal of Veterinary Diagnostic Investigation 19 (5) 552-557.
Fryer HR, Baylis M, Sivam K, McLean AR 2007
Quantifying the risk from ovine BSE and the impact of control strategies.
Proceedings of the Royal Society B 274 (1617) 1497-1503.
Gavier-Widen D, Noremark M, Langeveld JPM, Stack M, Biacabe AG, Vulin J, Chaplin M, Richt JA, Jacobs J, Acin C, Monleon E, Renstrom L, Klingeborn B, Baron TGM 2008
Bovine spongiform encephalopathy in Sweden: an H-type variant.
Journal of Veterinary Diagnostic Investigation 20 (1) 2-10.
Glover DG, Pollard BJ, Gonzalez L, Siso S, Kennedy D, Jeffrey M 2007
A non-invasive screen for infectivity in transmissible spongiform encephalopathies.
Gut 56 (9) 1329-1330.
Gonzalez L, Dagleish MP, Martin S, Dexter G, Steele P, Finlayson J, Jeffrey M 2008
Diagnosis of preclinical scrapie in live sheep by the immunohistochemical examination of rectal biopsies.
Veterinary Record 162 (13) 397-403.
Gonzalez L, Horton R, Ramsay D, Toomlik R, Leathers V, Tonelli Q, Dagleish MP, Jeffrey M, Terry L 2008
Adaptation and evaluation of a rapid test for the diagnosis of sheep scrapie in samples of rectal mucosa.
Journal of Veterinary Diagnostic Investigation 20 (2) 203-208.
Green DM, Del Rio Vilas VJ, Birch CPD, Johnson J, Kiss IZ, McCarthy ND, Kao RR 2007
Demographic risk factors for classical and atypical scrapie in Great Britain.
Journal of General Virology 88 (12) 3486-3492.
Griffin JK, Terry LA, Jackman R, Yousefi M, Cashman NR 2007
Decreased cell surface prion protein in mouse models of prion disease.
NeuroReport 18 (1) 1-6.
Horton RA, Allison GG, Jayasena D, Stevens PR, Clifford D, Everest S, Jackman R, Moorby JM 2008
Plasma glucose concentration is maintained during TSE infection of cattle and sheep.
Veterinary Research Communications 32 (2) 193-199.
Jeffrey M, Gonzalez L 2007
Classical sheep transmissible spongiform encephalopathies: pathogenesis, pathological phenotypes and clinical disease.
Neuropathology and Applied Neurobiology 33 (4) 373-394.
Jeffrey M, Gonzalez L 2007
Scrapie.
In: Aitken ID (ed); Diseases of Sheep, 4th ed., Blackwell Publishing, Oxford, 2007, 241-250.
Kuncheva LI, Del Rio Vilas VJ, Rodriguez JJ 2007
Diagnosing scrapie in sheep: a classification experiment.
Computers in Biology and Medicine 37 (8) 1194-1202.
Masujin K, Matthews D, Wells GAH, Mohri S, Yokoyama T 2007
Prions in the peripheral nerves of bovine spongiform encephalopathy-affected cattle.
Journal of General Virology 88 (6) 1850-1858.
McIntyre KM, Del Rio Vilas VJ, Gubbins S 2008
No temporal trends in the prevalence of atypical scrapie in British sheep, 2002-2006.
BMC Veterinary Research 4:13.
Owen JP, Rees HC, Maddison BC, Terry LA, Thorne L, Jackman R, Whitelam GC, Gough KC 2007
Molecular profiling of ovine prion diseases by using thermolysin-resistant PrPSc and endogenous C2 PrP fragments.
Journal of Virology 81 (19) 10532-10539.
Philipp WJ, Groth D, Giles K, Vodrazka P, Schimmel H, Feyssaguet M; Toomik R, Schacher P, Osman AA, Lachmann I, Wear A, Arsac JN, Prusiner SB 2007
Transgenic mouse brains for the evaluation and quality control of BSE tests.
Biological Chemistry 388 (3) 349-354.
Saunders GC, Griffiths PC, Cawthraw S, Tout AC, Wiener P, Woolliams JA, Williams JL, Windl O 2007
Polymorphisms of the prion protein gene coding region in born-after-the-reinforced-ban (BARB) bovine spongiform encephalopathy cattle in Great Britain.
Journal of General Virology 88 (4) 1374-1378.
Saunders GC, Horigan V, Tout AC, Windl O 2007
Identification of a proteinase K resistant protein for use as an internal positive control marker in PrP Western blotting.
Research in Veterinary Science 83 (2) 157-164.
Simmons MM, Konold T, Simmons HA, Spencer YI, Lockey R, Spiropoulos J, Everitt S, Clifford D 2007
Experimental transmission of atypical scrapie to sheep.
BMC Veterinary Research (3) 20.
Spiropoulos J, Casalone C, Caramelli M, Simmons MM 2007
Immunohistochemistry for PrPSc in natural scrapie reveals patterns which are associated with the PrP genotype.
Neuropathology and Applied Neurobiology 33 (4) 398-409.
Terry LA, Jenkins R, Thorne L, Everest SJ, Chaplin MJ, Davis LA, Stack MJ 2007
First case of H-type bovine spongiform encephalopathy identified in Great Britain.
Veterinary Record 160 (25) 873-875.
Wolfe LL, Spraker TR, Gonzalez L, Dagleish MP, Sirochman TM, Brown JC, Jeffrey M, Miller MW 2007
PrPCWD in rectal lymphoid tissue of deer (Odocoileus spp.).
Journal of General Virology 88 (7) 2078-2082.
Xiang W, Hummel M, Mitteregger G, Pace C, Windl O, Mansmann U, Kretzschmar HA 2007
Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model.
Journal of Neurochemistry 102 (3) 834-847.
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