Selected Papers by VLA Scientists
Transmissible Spongiform Encephalopathies
Birkmann E, Schafer O, Weinmann N,
Dumpitak C, Beekes M, Jackman R,
Thorne L, Riesner D 2006
Detection of prion particles in samples of
BSE and scrapie by fluorescence correlation
spectroscopy without proteinase K digestion.
Biological Chemistry 387 (1) 95-102.
Casalone C, Caramelli M, Crescio MI,
Spencer YI, Simmons MM 2006
BSE immunohistochemical patterns in the
brainstem: a comparison between UK and
Italian cases.
Acta Neuropathologica 111 (5) 444-449.
Charlton AJ, Jones S, Heasman L,
Davis AM, Dennis MJ 2006
Scrapie infection alters the distribution of
plasma metabolites in diseased Cheviot
sheep indicating a change in energy
metabolism.
Research in Veterinary Science 80 (3) 275-
280.
Del Rio Vilas VJ, Guitian J, Pfeiffer DU,
Wilesmith JW 2006
Analysis of data from the passive surveillance
of scrapie in Great Britain between 1993 and
2002.
Veterinary Record 159 (24) 799-804.
Eaton SL, Rocchi M, Gonzalez L, Hamilton S, Finlayson J, Sales J, Jeffrey M, Steele PJ, Dagleish MP, Rodger SM, Reid HW,
Chianini F 2007
Immunological differences between
susceptible and resistant sheep during the
preclinical phase of scrapie infection.
Journal of General Virology 88 (4) 1384-
1391.
Everest SJ, Thorne LT, Hawthorn JA,
Jenkins R, Hammersley C,
Ramsay AM, Hawkins SA, Venables L,
Flynn L, Sayers R, Kilpatrick J, Sach A,
Hope J, Jackman R 2006
No abnormal prion protein detected in the
milk of cattle infected with the bovine
spongiform encephalopathy agent.
Journal of General Virology 87 (8) 2433-
2441.
Gonzalez L, Chianini F, Martin S, Siso S, Gibbard L, Reid HW, Jeffrey M 2007
Comparative titration of experimental ovine
BSE infectivity in sheep and mice.
Journal of General Virology 88 (2) 714-717.
Hicks DJ, Johnson L, Mitchell SM,
Gough J, Cooley WA, La Ragione RM,
Spencer YI, Wangoo A 2006
Evaluation of zinc salt based fixatives for
preserving antigenic determinants for
immunohistochemical demonstration of
murine immune system cell markers.
Biotechnic and Histochemistry 81 (1) 23-30.
Hornlimann B, Doher MG, Matthews D, MacDiarmid SC 2007
Introduction to surveillance for animal prion
diseases.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 382-388.
Hornlimann B, Kretzschmar H, Will RG,
Windl O, Budka H 2007
Introduction to surveillance for human prion
diseases.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 339-346.
Hornlimann B, Riesner D, Kretzschmar H,
Will RG, MacDiarmid SC, Wells GAH, Alpers MP 2007
Historical introduction.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 3-27.
Hornlimann B, Ryan J, MacDiarmid SC
2007
The course of the BSE epidemic -
retrospective epidemiological considerations.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 449-463.
Jackman R, Everest DJ, Schmerr MJ,
Khawaja M, Keep P, Docherty J 2006
Evaluation of a preclinical blood test for
scrapie in sheep using immunocapillary
electrophoresis.
Journal of AOAC International 89 (3) 720-
727.
Jeffrey M, Gonzalez L, Espenes A,
Press CM, Martin S, Chaplin M,
Davis L, Landsverk T, MacAldowie C,
Eaton S, McGovern G 2006
Transportation of prion protein across the
intestinal mucosa of scrapie-susceptible and
scrapie-resistant sheep.
Journal of Pathology 209 (1) 4-14.
Jeffrey M, Martin S, Gonzalez L, Foster J, Langeveld JPM, Zijderveld FG van,
Grassi J, Hunter N 2006
Immunohistochemical features of PrPd
accumulation in natural and experimental
goat transmissible spongiform
encephalopathies.
Journal of Comparative Pathology 134 (2-3)
171-181.
Konold T, Lee YH, Stack MJ,
Horrocks C, Green RB, Chaplin M,
Simmons MM, Hawkins SAC,
Lockey R, Spiropoulos J, Wilesmith JW,
Wells GAH 2006
Different prion disease phenotypes result
from inoculation of cattle with two
temporally separated sources of sheep
scrapie from Great Britain.
BMC Veterinary Research 2 (31).
Konold T, Davis A, Bone G, Bracegirdle J,
Everitt S, Chaplin M, Saunders GC,
Cawthraw S, Simmons MM 2007
Clinical findings in two cases of atypical
scrapie in sheep: a case report.
BMC Veterinary Research 3 (2).
Konold T, Sivam SK, Ryan J,
Gubbins S, Laven R, Howe MJH 2006
Analysis of clinical signs associated with
bovine spongiform encephalopathy in
casualty slaughter cattle.
Veterinary Journal 171 (3) 438-444.
McIntyre KM, Gubbins S, Sivam SK, Baylis M 2006
Flock-level risk factors for scrapie in Great
Britain: analysis of a 2002 anonymous postal
survey.
BMC Veterinary Research 2 (25)
doi:10.1186/1746-6148-2-25.
Piening N, Nonno R, Di Bari M, Walter S,
Windl O, Agrimi U, Kretzschmar HA,
Bertsch U 2006
Conversion efficiency of bank vole prion
protein in vitro is determined by residues 155
and 170, but does not correlate with the
high susceptibility of bank voles to sheep
scrapie in vivo.
Journal of Biological Chemistry 281 (14)
9373-9384.
Saegerman C, Speybroeck N,
Vanopdenbosch E, Wilesmith JW, Berkvens D 2006
Trends in age at detection in cases of bovine
spongiform encephalopathy in Belgium: an
indicator of the epidemic curve.
Veterinary Record 159 (18) 583-587.
Saunders GC, Cawthraw S,
Mountjoy SJ, Hope J, Windl O 2006
PrP genotypes of atypical scrapie cases in
Great Britain.
Journal of General Virology 87 (11) 3141-
3149.
Saunders GC, Griffiths PC,
Cawthraw S, Tout AC, Wiener P,
Woolliams JA, Williams JL, Windl O 2007
Polymorphisms of the prion protein gene
coding region in born-after-the-reinforcedban
(BARB) bovine spongiform
encephalopathy cattle in Great Britain.
Journal of General Virology 88 (4) 1374-
1378.
Schicker E, Braun U, Hornlimann B,
Konold T 2007
Clinical findings in bovine spongiform
encephalopathy.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 389-397.
Siso S, Gonzalez L, Houston F, Hunter N,
Martin S, Jeffrey M 2006
The neuropathologic phenotype of
experimental ovine BSE is maintained after
blood transfusion.
Blood 108 (2) 745-748.
Sivam SK, Baylis M, Gravenor MB,
Gubbins S 2006
Descriptive analysis of the results of an
anonymous postal survey of the occurrence
of scrapie in Great Britain in 2002.
Veterinary Record 158 (15) 501-506.
Stack M, Jeffrey M, Gubbins S,
Grimmer S, Gonzalez L, Martin S,
Chaplin M, Webb P, Simmons M,
Spencer Y, Bellerby P, Hope J, Wilesmith J, Matthews D 2006
Monitoring for bovine spongiform
encephalopathy in sheep in Great Britain,
1998-2004.
Journal of General Virology 87 (7) 2099-
2107.
Tongue SC, Pfeiffer DU, Heasman L,
Simmons H, Ryder SJ 2006
PrP genotype and lamb birth weight in a
scrapie-free environment: is there an
association?
Livestock Science 105 (1-3) 120-128.
Tongue SC, Pfeiffer DU, Wilesmith JW
2006
Descriptive spatial analysis of scrapieaffected
flocks in Great Britain between
January 1993 and December 2002.
Veterinary Record 159 (6) 165-170.
Vollmert C, Windl O, Xiang W,
Rosenberger A, Zerr I, Wichmann HE,
Bickeboller H; Illig T, KORA group;
Kretzschmar HA 2006
Significant association of a M129V
independent polymorphism in the 5’ UTR of
the PRNP gene with sporadic Creutzfeldt-
Jakob disease in a large German case-control
study.
Journal of Medical Genetics 43 (10) E53.
Wells GAH, Konold T, Arnold ME, Austin AR, Hawkins SAC, Stack M,
Simmons MM, Lee YH, Gavier-Widen D,
Dawson M, Wilesmith JW 2007
Bovine spongiform encephalopathy: the
effect of oral exposure dose on attack rate
and incubation period in cattle.
Journal of General Virology 88 (4) 1363-
1373.
Wells GAH, Hawkins SAC, Pohlenz J,
Matthews D 2007
Portrait of experimental BSE in pigs.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 275-278.
Wells GAH, Pohlenz J, Hawkins SAC,
Matthews D 2007
Portrait of a spongiform encephalopathy in
birds and the transmissibility of mammalian
prion diseases to birds.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 279-283.
Wells GAH, Ryder SJ, Hadlow WJ 2007
The pathology of prion diseases in animals.
In: Hornlimann B (ed), Riesner D (ed),
Kretzschmar H (ed); Prions in humans and
animals, De Gruyter, Berlin, 2007, 315-327.
