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Working for public and animal health
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VLA Annual Review 03/04
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Selected papers by VLA Scientists
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Cows in field
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Transmissible Spongiform Encephalopathies (TSE)
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Arnold M, Wilesmith J 2003
Modelling studies on bovine spongiform encephalopathy occurrence to assist in the review of the over 30 months rule in Great Britain.
Proceedings of the Royal Society of London Series B 270 (1529) 2141-2145

Bradley R 2003
BSE risks for humans consuming beef and beef products: how any risks are managed.
Veterinary Research Communications 27 (Supp 1) 15-23

Ersdal C, Simmons MM, Goodsir C, Martin S, Jeffrey M 2003
Sub-cellular pathology of scrapie: coated pits are increased in PrP codon 136 alanine homozygous scrapie-affected sheep.
Acta Neuropathologica 106 (1) 17-28

Gonzalez L, Martin S, Jeffrey M 2003
Distinct profiles of PrPd immunoreactivity in the brain of scrapie- and BSE-infected sheep: implications for differential cell
targeting and PrP processing.
Journal of General Virology 84 (5) 1339-1350

Gubbins S, Simmons MM, Sivam K, Webb CR, Hoinville LJ 2003
Prevalence of scrapie infection in Great Britain: interpreting the results of the 1997-1998 abattoir survey.
Proceedings of the Royal Society of London B 270 (1527) 1919-1924

Hamir AN, Miller JM, Cutlip RC, Stack MJ, Chaplin MJ, Jenny AL, Williams ES 2003
Experimental inoculation of scrapie and chronic wasting disease agents in raccoons (Procyon lotor).
Veterinary Record 153 (4) 121-123

Hamir AN, Miller JM, O’Rourke KI, Bartz JC, Stack MJ, Chaplin MJ 2004
Transmission of transmissible mink encephalopathy to racoons (Procyon lotor) by intracerebral inoculation.
Journal of Veterinary Diagnostic Investigation 16 (1) 57-63

Heggebo R, Gonzalez L, Press CM, Gunnes G, Espenes A, Jeffrey M 2003
Disease-associated PrP in the enteric nervous system of scrapie-affected Suffolk sheep.
Journal of General Virology 84 (5) 1327-1338

Houston F, Goldmann W, Chong A, Jeffrey M, Gonzalez L, Foster J, Parnham D, Hunter N 2003
BSE in sheep bred for resistance to infection.
Nature 423 (6939) 498

Jackman R, Schmerr MJ 2003
Analysis of the performance of antibody capture methods using fluorescent peptides with capillary zone electrophoresis with laser-induced fluorescence.
Electrophoresis 24 (5) 892-896

Ligios C, Viglietti A, Carta P, Dexter G, Agrimi U, Simmons MM 2004
Clinicopathological findings in sheep from Sardinia showing neurological signs of disease.
Veterinary Record 154 (12) 365-370

Matthews D 2003
BSE: a global update.
Journal of Applied Microbiology 94 (Supplement 32) 120S-125S

McGovern G, Brown KL, Bruce ME, Jeffrey M 2004
Murine scrapie infection causes an abnormal germinal centre reaction in the spleen.
Journal of Comparative Pathology 130 (2-3) 181-194

Ocana MF, Neubert H, Przyborowska A, Parker R, Bramley P, Halket J, Patel R 2004
BSE control: detection of gelatine-derived peptides in animal feed by mass spectrometry.
Analyst 129 (2) 111-115

Sivam SK, Baylis M, Gravenor MB, Gubbins S, Wilesmith JW 2003
Results of a postal survey in 2002 into the occurrence of scrapie in Great Britain.
Veterinary Record 153 (25) 782-783

Terry LA, Marsh S, Ryder SJ, Hawkins SAC, Wells GAH, Spencer YI 2003
Detection of disease-specific PrP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy.
Veterinary Record 152 (13) 387-392

Thuring CMA, Erkens JHF, Jacobs JG, Bossers A, Van Keulen LJM, Garssen GJ, Van Zijderveld FG, Ryder SJ, Groschup MH, Sweeney T, Langeveld JPM 2004
Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein.
Journal of Clinical Microbiology 42 (3) 972-980

Tongue SC, Wilesmith J, Cook CJ 2004
Frequencies of prion protein (PrP) genotypes and distribution of ages in 15 scrapie-affected flocks in Great Britain.
Veterinary Record 154 (1) 9-16

Wells GAH 2003
Pathogenesis of BSE.
Veterinary Research Communications 27 (supp 1) 25-28

Wrathall AE, Simmons HA, Bowles DJ, Jones S 2004
Biosecurity strategies for conserving valuable livestock genetic resources.
Reproduction, Fertility and Development (16) 103-112

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